2p3d: Difference between revisions

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-{{Seed}}
-[[Image:2p3d.png|left|200px]]
-<!--
+==Crystal Structure of the multi-drug resistant mutant subtype F HIV protease complexed with TL-3 inhibitor==
-The line below this paragraph, containing "STRUCTURE_2p3d", creates the "Structure Box" on the page.
+<StructureSection load='2p3d' size='340' side='right'caption='[[2p3d]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2p3d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P3D FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3TL:BENZYL+[(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-DIBENZYL-8,9-DIHYDROXY-1,16-DIMETHYL-4,13-BIS(1-METHYLETHYL)-2,5,12,15,18-PENTAOXO-20-PHENYL-19-OXA-3,6,11,14,17-PENTAAZAICOS-1-YL]CARBAMATE'>3TL</scene></td></tr>
-{{STRUCTURE_2p3d|  PDB=2p3d  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3d OCA], [https://pdbe.org/2p3d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p3d RCSB], [https://www.ebi.ac.uk/pdbsum/2p3d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3d ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q7SRY5_9HIV1 Q7SRY5_9HIV1]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/2p3d_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p3d ConSurf].
+<div style="clear:both"></div>
-===Crystal Structure of the multi-drug resistant mutant subtype F HIV protease complexed with TL-3 inhibitor===
+==See Also==
+*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_17467738}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 17467738 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_17467738}}
-==About this Structure==
-P3D is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3D OCA].
-==Reference==
-<ref group="xtra">PMID:17467738</ref><references group="xtra"/>
-[[Category: HIV-1 retropepsin]]
 [[Category: Human immunodeficiency virus 1]]
-[[Category: Gustchina, A.]]
+[[Category: Large Structures]]
-[[Category: Krauchenco, S.]]
+[[Category: Gustchina A]]
-[[Category: Martins, N H.]]
+[[Category: Krauchenco S]]
-[[Category: Polikarpov, I.]]
+[[Category: Martins NH]]
-[[Category: Sanches, M.]]
+[[Category: Polikarpov I]]
-[[Category: Wlodawer, A.]]
+[[Category: Sanches M]]
-[[Category: Hydrolase]]
+[[Category: Wlodawer A]]
-[[Category: Multi-drug resistant mutant subtype f hiv protease]]
-[[Category: Non-b hiv protease]]
-[[Category: Protease-inhibitor complex]]
-[[Category: Tl-3 inhibitor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Apr 19 08:51:03 2009''