2ov7: Difference between revisions

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[[Image:2ov7.png|left|200px]]


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==The first domain of the ribosomal protein L1 from Thermus thermophilus==
The line below this paragraph, containing "STRUCTURE_2ov7", creates the "Structure Box" on the page.
<StructureSection load='2ov7' size='340' side='right'caption='[[2ov7]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ov7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OV7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OV7 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ov7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ov7 OCA], [https://pdbe.org/2ov7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ov7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ov7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ov7 ProSAT]</span></td></tr>
{{STRUCTURE_2ov7| PDB=2ov7 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/RL1_THET8 RL1_THET8] Directly binds to 23S rRNA. Forms what is known as the L1 stalk, which protrudes beyond the 70S ribosome surface. The stalk is preferentially stabilized in 70S versus 50S crystals. Interacts with the E site tRNA, blocking the exit path. This blockage implies that this section of the ribosome must be able to move to release the deacetylated tRNA.[HAMAP-Rule:MF_01318_B]  Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA (By similarity).[HAMAP-Rule:MF_01318_B]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ov/2ov7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ov7 ConSurf].
<div style="clear:both"></div>


===The first domain of the ribosomal protein L1 from Thermus thermophilus===
==See Also==
 
*[[Ribosomal protein L1|Ribosomal protein L1]]
 
__TOC__
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_17962298}}
 
==About this Structure==
2OV7 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OV7 OCA].
 
==Reference==
<ref group="xtra">PMID:17962298</ref><references group="xtra"/>
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Davydova, N.]]
[[Category: Davydova N]]
[[Category: Garber, M.]]
[[Category: Garber M]]
[[Category: Kljashtorny, V.]]
[[Category: Kljashtorny V]]
[[Category: Nevskaya, N.]]
[[Category: Nevskaya N]]
[[Category: Nikonov, S.]]
[[Category: Nikonov S]]
[[Category: Tishchenko, S.]]
[[Category: Tishchenko S]]
[[Category: Ribosomal protein l1]]
[[Category: Thermus thermophilus]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:43:26 2009''

Latest revision as of 12:06, 21 February 2024

The first domain of the ribosomal protein L1 from Thermus thermophilusThe first domain of the ribosomal protein L1 from Thermus thermophilus

Structural highlights

2ov7 is a 3 chain structure with sequence from Thermus thermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RL1_THET8 Directly binds to 23S rRNA. Forms what is known as the L1 stalk, which protrudes beyond the 70S ribosome surface. The stalk is preferentially stabilized in 70S versus 50S crystals. Interacts with the E site tRNA, blocking the exit path. This blockage implies that this section of the ribosome must be able to move to release the deacetylated tRNA.[HAMAP-Rule:MF_01318_B] Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA (By similarity).[HAMAP-Rule:MF_01318_B]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2ov7, resolution 2.30Å

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OCA
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