2kin: Difference between revisions

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-[[Image:2kin.png|left|200px]]
-<!--
+==KINESIN (MONOMERIC) FROM RATTUS NORVEGICUS==
-The line below this paragraph, containing "STRUCTURE_2kin", creates the "Structure Box" on the page.
+<StructureSection load='2kin' size='340' side='right'caption='[[2kin]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2kin]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The April 2005 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Kinesin''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2005_4 10.2210/rcsb_pdb/mom_2005_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KIN FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_2kin|  PDB=2kin  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kin OCA], [https://pdbe.org/2kin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kin RCSB], [https://www.ebi.ac.uk/pdbsum/2kin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kin ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/KIF5C_RAT KIF5C_RAT] Microtubule-associated force-producing protein that may play a role in organelle transport (By similarity). Has ATPase activity (PubMed:27452403). Involved in synaptic transmission (By similarity). Mediates dendritic trafficking of mRNAs (By similarity). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (PubMed:23576431).[UniProtKB:O60282][UniProtKB:P28738]<ref>PMID:23576431</ref> <ref>PMID:27452403</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ki/2kin_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kin ConSurf].
+<div style="clear:both"></div>
-'''KINESIN (MONOMERIC) FROM RATTUS NORVEGICUS'''
+==See Also==
+*[[Kinesin 3D Structures|Kinesin 3D Structures]]
+== References ==
-{{ABSTRACT_9405049}}
+<references/>
+__TOC__
-==About this Structure==
+</StructureSection>
-KIN is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The following page contains interesting information on the relation of 2KIN with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb64_1.html Kinesin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KIN OCA].
 [[Category: Kinesin]]
-[[Category: Protein complex]]
+[[Category: Large Structures]]
+[[Category: RCSB PDB Molecule of the Month]]
 [[Category: Rattus norvegicus]]
-[[Category: Biou, V.]]
+[[Category: Biou V]]
-[[Category: Brady, S T.]]
+[[Category: Brady ST]]
-[[Category: Kozielski, F.]]
+[[Category: Kozielski F]]
-[[Category: Mandelkow, E.]]
+[[Category: Mandelkow E]]
-[[Category: Mandelkow, E M.]]
+[[Category: Mandelkow E-M]]
-[[Category: Marx, A.]]
+[[Category: Marx A]]
-[[Category: Muller, J.]]
+[[Category: Muller J]]
-[[Category: Sack, S.]]
+[[Category: Sack S]]
-[[Category: Thormahlen, M.]]
+[[Category: Thormahlen M]]
-[[Category: Cytoskeleton]]
-[[Category: Motor protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 18:19:46 2008''