2izf: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:2izf.png|left|200px]]
-<!--
+==STREPTAVIDIN-BIOTIN PH 4.0 I222 COMPLEX==
-The line below this paragraph, containing "STRUCTURE_2izf", creates the "Structure Box" on the page.
+<StructureSection load='2izf' size='340' side='right'caption='[[2izf]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2izf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IZF FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_2izf|  PDB=2izf  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2izf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izf OCA], [https://pdbe.org/2izf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2izf RCSB], [https://www.ebi.ac.uk/pdbsum/2izf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2izf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iz/2izf_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2izf ConSurf].
+<div style="clear:both"></div>
-===STREPTAVIDIN-BIOTIN PH 4.0 I222 COMPLEX===
+==See Also==
+*[[Avidin 3D structures|Avidin 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_9405158}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 9405158 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_9405158}}
-==About this Structure==
-IZF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZF OCA].
-==Reference==
-Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH., Katz BA, J Mol Biol. 1997 Dec 19;274(5):776-800. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9405158 9405158]
-[[Category: Single protein]]
 [[Category: Streptomyces avidinii]]
-[[Category: Katz, B A.]]
+[[Category: Katz BA]]
-[[Category: Biotin-binding protein]]
-[[Category: Streptavidin-biotin]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:38:32 2008''