2i6v: Difference between revisions

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[[Image:2i6v.png|left|200px]]


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==PDZ domain of EpsC from Vibrio cholerae, residues 219-305==
The line below this paragraph, containing "STRUCTURE_2i6v", creates the "Structure Box" on the page.
<StructureSection load='2i6v' size='340' side='right'caption='[[2i6v]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2i6v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I6V FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i6v OCA], [https://pdbe.org/2i6v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i6v RCSB], [https://www.ebi.ac.uk/pdbsum/2i6v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i6v ProSAT]</span></td></tr>
{{STRUCTURE_2i6v| PDB=2i6v |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/GSPC_VIBCH GSPC_VIBCH] Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity). Required for secretion of cholera toxin through the outer membrane.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/2i6v_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i6v ConSurf].
<div style="clear:both"></div>


===PDZ domain of EpsC from Vibrio cholerae, residues 219-305===
==See Also==
 
*[[General secretion pathway protein 3D structures|General secretion pathway protein 3D structures]]
 
__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_16978643}}
 
==About this Structure==
2I6V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6V OCA].
 
==Reference==
Structural and functional studies of EpsC, a crucial component of the type 2 secretion system from Vibrio cholerae., Korotkov KV, Krumm B, Bagdasarian M, Hol WG, J Mol Biol. 2006 Oct 20;363(2):311-21. Epub 2006 Aug 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16978643 16978643]
[[Category: Single protein]]
[[Category: Vibrio cholerae]]
[[Category: Vibrio cholerae]]
[[Category: Bagdasarian, M.]]
[[Category: Bagdasarian M]]
[[Category: Hol, W G.J.]]
[[Category: Hol WGJ]]
[[Category: Korotkov, K V.]]
[[Category: Korotkov KV]]
[[Category: Krumm, B.]]
[[Category: Krumm B]]
[[Category: Epsc]]
[[Category: General secretion pathway]]
[[Category: Gspc]]
[[Category: Pdz domain]]
[[Category: Type 2 secretion system]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:53:32 2008''

Latest revision as of 12:01, 21 February 2024

PDZ domain of EpsC from Vibrio cholerae, residues 219-305PDZ domain of EpsC from Vibrio cholerae, residues 219-305

Structural highlights

2i6v is a 1 chain structure with sequence from Vibrio cholerae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.63Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GSPC_VIBCH Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity). Required for secretion of cholera toxin through the outer membrane.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2i6v, resolution 1.63Å

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