2i4t: Difference between revisions

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{{Seed}}
[[Image:2i4t.png|left|200px]]


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==Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A==
The line below this paragraph, containing "STRUCTURE_2i4t", creates the "Structure Box" on the page.
<StructureSection load='2i4t' size='340' side='right'caption='[[2i4t]], [[Resolution|resolution]] 2.74&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2i4t]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichomonas_vaginalis Trichomonas vaginalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I4T FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.74&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UA2:3,4-PYRROLIDINEDIOL,2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)-2S,3S,4R,5R'>UA2</scene></td></tr>
{{STRUCTURE_2i4t| PDB=2i4t |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i4t OCA], [https://pdbe.org/2i4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i4t RCSB], [https://www.ebi.ac.uk/pdbsum/2i4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i4t ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A2E7Y6_TRIV3 A2E7Y6_TRIV3]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i4/2i4t_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i4t ConSurf].
<div style="clear:both"></div>


===Crystal stucture of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A===
==See Also==
 
*[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_17223688}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 17223688 is the PubMed ID number.
[[Category: Trichomonas vaginalis]]
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[[Category: Almo SC]]
{{ABSTRACT_PUBMED_17223688}}
[[Category: Rinaldo-Matthis A]]
 
[[Category: Schramm VL]]
==About this Structure==
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4T OCA].
 
==Reference==
Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues., Rinaldo-Matthis A, Wing C, Ghanem M, Deng H, Wu P, Gupta A, Tyler PC, Evans GB, Furneaux RH, Almo SC, Wang CC, Schramm VL, Biochemistry. 2007 Jan 23;46(3):659-68. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17223688 17223688]
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Almo, S C.]]
[[Category: Rinaldo-Matthis, A.]]
[[Category: Schramm, V L.]]
[[Category: Purine nucleoside phosphorylase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:21:49 2008''

Latest revision as of 12:01, 21 February 2024

Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-ACrystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A

Structural highlights

2i4t is a 3 chain structure with sequence from Trichomonas vaginalis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.74Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

A2E7Y6_TRIV3

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2i4t, resolution 2.74Å

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