8skr: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
m Protected "8skr" [edit=sysop:move=sysop]
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 8skr is ON HOLD
==human liver mitochondrial Aspartate aminotransferase==
 
<StructureSection load='8skr' size='340' side='right'caption='[[8skr]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
Authors: Zhang, Z., Tringides, M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8skr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SKR FirstGlance]. <br>
Description: human liver mitochondrial Aspartate aminotransferase
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.99&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
[[Category: Tringides, M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8skr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8skr OCA], [https://pdbe.org/8skr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8skr RCSB], [https://www.ebi.ac.uk/pdbsum/8skr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8skr ProSAT]</span></td></tr>
[[Category: Zhang, Z]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/AATM_HUMAN AATM_HUMAN] Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.<ref>PMID:9537447</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Tringides M]]
[[Category: Zhang Z]]

Latest revision as of 11:58, 21 February 2024

human liver mitochondrial Aspartate aminotransferasehuman liver mitochondrial Aspartate aminotransferase

Structural highlights

8skr is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.99Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AATM_HUMAN Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.[1]

References

  1. ↑ Zhou SL, Gordon RE, Bradbury M, Stump D, Kiang CL, Berk PD. Ethanol up-regulates fatty acid uptake and plasma membrane expression and export of mitochondrial aspartate aminotransferase in HepG2 cells. Hepatology. 1998 Apr;27(4):1064-74. PMID:9537447 doi:http://dx.doi.org/10.1002/hep.510270423

8skr, resolution 2.99Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=8skr&oldid=4061728"