3nj5: Difference between revisions

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[[Image:3nj5.jpg|left|200px]]


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==Crystal structure of chicken IL-1 hydrophobic cavity mutant 157==
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<StructureSection load='3nj5' size='340' side='right'caption='[[3nj5]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3nj5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NJ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NJ5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nj5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nj5 OCA], [https://pdbe.org/3nj5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nj5 RCSB], [https://www.ebi.ac.uk/pdbsum/3nj5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nj5 ProSAT]</span></td></tr>
{{STRUCTURE_3nj5|  PDB=3nj5  |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753]


===Crystal structure of chicken IL-1 hydrophobic cavity mutant 157===
==See Also==
 
*[[Interleukin 3D structures|Interleukin 3D structures]]
 
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{{ABSTRACT_PUBMED_21288573}}
 
==About this Structure==
[[3nj5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NJ5 OCA].
 
==Reference==
<ref group="xtra">PMID:021288573</ref><references group="xtra"/>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Chen, Y W.]]
[[Category: Large Structures]]
[[Category: Yin, H S.]]
[[Category: Chen YW]]
[[Category: Chicken]]
[[Category: Yin HS]]
[[Category: Cytokine]]
[[Category: Hydrophobic cavity mutant]]
[[Category: Interleukin-1 beta]]

Latest revision as of 13:00, 14 February 2024

Crystal structure of chicken IL-1 hydrophobic cavity mutant 157Crystal structure of chicken IL-1 hydrophobic cavity mutant 157

Structural highlights

3nj5 is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.67Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

O73909_CHICK Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753]

See Also

3nj5, resolution 1.67Å

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