8icd: Difference between revisions

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-[[Image:8icd.png|left|200px]]
-{{STRUCTURE_8icd|  PDB=8icd  |  SCENE=  }}
+==REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE==
+<StructureSection load='8icd' size='340' side='right'caption='[[8icd]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-===REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8icd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The September 2010 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Isocitrate Dehydrogenase''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2010_9 10.2210/rcsb_pdb/mom_2010_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ICD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ICD FirstGlance]. <br>
-{{ABSTRACT_PUBMED_2204109}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ICT:ISOCITRIC+ACID'>ICT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8icd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8icd OCA], [https://pdbe.org/8icd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8icd RCSB], [https://www.ebi.ac.uk/pdbsum/8icd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8icd ProSAT]</span></td></tr>
-[[8icd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The September 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Isocitrate Dehydrogenase''  by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_9 10.2210/rcsb_pdb/mom_2010_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ICD OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/IDH_ECOLI IDH_ECOLI]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ic/8icd_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=8icd ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Ferguson sandbox 1|Ferguson sandbox 1]]
+*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
-*[[Isocitrate dehydrogenase|Isocitrate dehydrogenase]]
+__TOC__
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:002204109</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
 [[Category: Isocitrate Dehydrogenase]]
+[[Category: Large Structures]]
 [[Category: RCSB PDB Molecule of the Month]]
-[[Category: Dean, A M.]]
+[[Category: Dean AM]]
-[[Category: Hurley, J H.]]
+[[Category: Hurley JH]]
-[[Category: Koshlandjunior, D E.]]
+[[Category: Koshlandjunior DE]]
-[[Category: Sohl, J L.]]
+[[Category: Sohl JL]]
-[[Category: Stroud, R M.]]
+[[Category: Stroud RM]]