7u5c: Difference between revisions
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==== | ==Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state== | ||
<StructureSection load='7u5c' size='340' side='right'caption='[[7u5c]]' scene=''> | <StructureSection load='7u5c' size='340' side='right'caption='[[7u5c]], [[Resolution|resolution]] 4.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7u5c]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7U5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7U5C FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u5c OCA], [https://pdbe.org/7u5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u5c RCSB], [https://www.ebi.ac.uk/pdbsum/7u5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u5c ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.6Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u5c OCA], [https://pdbe.org/7u5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u5c RCSB], [https://www.ebi.ac.uk/pdbsum/7u5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u5c ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PRI2_HUMAN PRI2_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. | |||
==See Also== | |||
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | |||
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Bush MW]] | ||
[[Category: Cai SW]] | |||
[[Category: Nudler E]] | |||
[[Category: Svetlov V]] | |||
[[Category: Walz T]] | |||
[[Category: Zinder JC]] | |||
[[Category: De Lange T]] | |||
Latest revision as of 12:38, 14 February 2024
Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment stateCryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state
Structural highlights
FunctionPRI2_HUMAN DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. See Also |
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