2huc: Difference between revisions
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==Structural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein Variants== | |||
<StructureSection load='2huc' size='340' side='right'caption='[[2huc]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2huc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HUC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HUC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2huc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2huc OCA], [https://pdbe.org/2huc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2huc RCSB], [https://www.ebi.ac.uk/pdbsum/2huc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2huc ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PHLC_BACCE PHLC_BACCE] Required, with sphingomyelinase, to effect target cell lysis (hemolysis). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hu/2huc_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2huc ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[Phospholipase C|Phospholipase C]] | |||
__TOC__ | |||
</StructureSection> | |||
[[ | |||
[[Category: Bacillus cereus]] | [[Category: Bacillus cereus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Antikainen NM]] | ||
[[Category: | [[Category: Benfield AP]] | ||
[[Category: | [[Category: Martin SF]] | ||
Latest revision as of 12:34, 14 February 2024
Structural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein VariantsStructural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein Variants
Structural highlights
FunctionPHLC_BACCE Required, with sphingomyelinase, to effect target cell lysis (hemolysis). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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