2hdd: Difference between revisions

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{{Seed}}
[[Image:2hdd.png|left|200px]]


<!--
==ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX==
The line below this paragraph, containing "STRUCTURE_2hdd", creates the "Structure Box" on the page.
<StructureSection load='2hdd' size='340' side='right'caption='[[2hdd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2hdd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HDD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HDD FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hdd OCA], [https://pdbe.org/2hdd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hdd RCSB], [https://www.ebi.ac.uk/pdbsum/2hdd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hdd ProSAT]</span></td></tr>
{{STRUCTURE_2hdd|  PDB=2hdd  |  SCENE=  }}
</table>
 
== Function ==
===ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX===
[https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_9309220}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 9309220 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hd/2hdd_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_9309220}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hdd ConSurf].
2HDD is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HDD OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:9309220</ref><references group="xtra"/>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Ades, S E.]]
[[Category: Large Structures]]
[[Category: Chambers, K A.]]
[[Category: Ades SE]]
[[Category: Pabo, C O.]]
[[Category: Chambers KA]]
[[Category: Rould, M A.]]
[[Category: Pabo CO]]
[[Category: Sauer, R T.]]
[[Category: Rould MA]]
[[Category: Tucker-Kellogg, L.]]
[[Category: Sauer RT]]
[[Category: Dna binding]]
[[Category: Tucker-Kellogg L]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:14:42 2009''

Latest revision as of 12:32, 14 February 2024

ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEXENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX

Structural highlights

2hdd is a 4 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HMEN_DROME This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2hdd, resolution 1.90Å

Drag the structure with the mouse to rotate

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OCA
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