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==Crystal structure of the JUN BZIP homodimer complexed with AP-1 DNA== | ==Crystal structure of the JUN BZIP homodimer complexed with AP-1 DNA== | ||
<StructureSection load='2h7h' size='340' side='right' caption='[[2h7h]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2h7h' size='340' side='right'caption='[[2h7h]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2h7h]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2h7h]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Avian_sarcoma_virus Avian sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H7H FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<table> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h7h OCA], [https://pdbe.org/2h7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h7h RCSB], [https://www.ebi.ac.uk/pdbsum/2h7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h7h ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/JUN_AVIS1 JUN_AVIS1] This oncogene is the viral derivative of the AP-1 transcription factor. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h7/2h7h_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h7/2h7h_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h7h ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Avian sarcoma virus]] | [[Category: Avian sarcoma virus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Borovilos M]] | ||
[[Category: | [[Category: Cuff ME]] | ||
[[Category: | [[Category: Kim Y]] | ||
[[Category: | [[Category: Rajan SS]] | ||
Latest revision as of 12:31, 14 February 2024
Crystal structure of the JUN BZIP homodimer complexed with AP-1 DNACrystal structure of the JUN BZIP homodimer complexed with AP-1 DNA
Structural highlights
FunctionJUN_AVIS1 This oncogene is the viral derivative of the AP-1 transcription factor. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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