2gx8: Difference between revisions

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[[Image:2gx8.gif|left|200px]]


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==The Crystal Structure of Bacillus cereus protein related to NIF3==
The line below this paragraph, containing "STRUCTURE_2gx8", creates the "Structure Box" on the page.
<StructureSection load='2gx8' size='340' side='right'caption='[[2gx8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gx8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus_ATCC_14579 Bacillus cereus ATCC 14579]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GX8 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2gx8|  PDB=2gx8  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gx8 OCA], [https://pdbe.org/2gx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gx8 RCSB], [https://www.ebi.ac.uk/pdbsum/2gx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gx8 ProSAT], [https://www.topsan.org/Proteins/MCSG/2gx8 TOPSAN]</span></td></tr>
 
</table>
'''The Crystal Stucture of Bacillus cereus protein related to NIF3'''
== Function ==
 
[https://www.uniprot.org/uniprot/Q818H0_BACCR Q818H0_BACCR]  
 
== Evolutionary Conservation ==
==Overview==
[[Image:Consurf_key_small.gif|200px|right]]
YqfO of Bacillus cereus is a member of the widespread Nif3 family of proteins, which has been highlighted as an important target for structural genomics. The N- and C-terminal domains are conserved across the family and contain a dimetal-binding motif in a putative active site. YqfO contains an insert in the middle of the protein, present in a minority of bacterial family members. The structure of YqfO was determined at a resolution of 2.2 A and reveals conservation of the putative active site. It also reveals the previously unknown structure of the insert, which despite extremely limited sequence conservation, bears great similarity to PII, CutA, and a number of other trimeric regulatory proteins. Our results suggest that this domain acts as a signal sensor to regulate the still-unknown catalytic activity of the more-conserved domains.
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gx/2gx8_consurf.spt"</scriptWhenChecked>
2GX8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus_atcc_14579 Bacillus cereus atcc 14579]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GX8 OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==Reference==
  </jmolCheckbox>
The 2.2 A resolution crystal structure of Bacillus cereus Nif3-family protein YqfO reveals a conserved dimetal-binding motif and a regulatory domain., Godsey MH, Minasov G, Shuvalova L, Brunzelle JS, Vorontsov II, Collart FR, Anderson WF, Protein Sci. 2007 Jul;16(7):1285-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17586767 17586767]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gx8 ConSurf].
[[Category: Bacillus cereus atcc 14579]]
<div style="clear:both"></div>
[[Category: Single protein]]
__TOC__
[[Category: Anderson, W F.]]
</StructureSection>
[[Category: Brunzelle, J S.]]
[[Category: Bacillus cereus ATCC 14579]]
[[Category: Collart, F R.]]
[[Category: Large Structures]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Anderson WF]]
[[Category: Mcsg]]
[[Category: Brunzelle JS]]
[[Category: Minasov, G.]]
[[Category: Collart FR]]
[[Category: Shuvalova, L.]]
[[Category: Joachimiak A]]
[[Category: Vorontsov, I I.]]
[[Category: Minasov G]]
[[Category: Crystal structure]]
[[Category: Shuvalova L]]
[[Category: Mcsg]]
[[Category: Vorontsov II]]
[[Category: Midwest center for structural genomic]]
[[Category: Nif3 related protein]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Unknown function]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 22 22:24:10 2008''

Latest revision as of 12:30, 14 February 2024

The Crystal Structure of Bacillus cereus protein related to NIF3The Crystal Structure of Bacillus cereus protein related to NIF3

Structural highlights

2gx8 is a 3 chain structure with sequence from Bacillus cereus ATCC 14579. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

Q818H0_BACCR

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2gx8, resolution 2.20Å

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OCA
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