2gqs: Difference between revisions

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[[Image:2gqs.png|left|200px]]


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==SAICAR Synthetase Complexed with CAIR-Mg2+ and ADP==
The line below this paragraph, containing "STRUCTURE_2gqs", creates the "Structure Box" on the page.
<StructureSection load='2gqs' size='340' side='right'caption='[[2gqs]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gqs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GQS FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=C2R:5-AMINO-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC+ACID'>C2R</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_2gqs| PDB=2gqs |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gqs OCA], [https://pdbe.org/2gqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gqs RCSB], [https://www.ebi.ac.uk/pdbsum/2gqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gqs ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PUR7_ECOLI PUR7_ECOLI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/2gqs_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gqs ConSurf].
<div style="clear:both"></div>


===SAICAR Synthetase Complexed with CAIR-Mg2+ and ADP===
==See Also==
 
*[[SAICAR synthetase|SAICAR synthetase]]
 
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{{ABSTRACT_PUBMED_16687397}}
 
==About this Structure==
2GQS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQS OCA].
 
==Reference==
Nucleotide complexes of Escherichia coli phosphoribosylaminoimidazole succinocarboxamide synthetase., Ginder ND, Binkowski DJ, Fromm HJ, Honzatko RB, J Biol Chem. 2006 Jul 28;281(30):20680-8. Epub 2006 May 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16687397 16687397]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Phosphoribosylaminoimidazolesuccinocarboxamide synthase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Ginder ND]]
[[Category: Ginder, N D.]]
[[Category: Honzatko RB]]
[[Category: Honzatko, R B.]]
[[Category: Ade1]]
[[Category: Ade2]]
[[Category: Magnesium coordination]]
[[Category: Metal coordination]]
[[Category: Nucleotide complex]]
[[Category: Purc]]
 
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