2gih: Difference between revisions

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[[Image:2gih.png|left|200px]]


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==Q138F HincII bound to cognate DNA GTCGAC and Ca2+==
The line below this paragraph, containing "STRUCTURE_2gih", creates the "Structure Box" on the page.
<StructureSection load='2gih' size='340' side='right'caption='[[2gih]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gih]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GIH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_2gih|  PDB=2gih  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gih OCA], [https://pdbe.org/2gih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gih RCSB], [https://www.ebi.ac.uk/pdbsum/2gih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gih ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/T2C2_HAEIF T2C2_HAEIF] Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3.


===Q138F HincII bound to cognate DNA GTCGAC and Ca2+===
==See Also==
 
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
 
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The line below this paragraph, {{ABSTRACT_PUBMED_16675462}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_16675462}}
 
==About this Structure==
2GIH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIH OCA].
 
==Reference==
Alteration of sequence specificity of the type II restriction endonuclease HincII through an indirect readout mechanism., Joshi HK, Etzkorn C, Chatwell L, Bitinaite J, Horton NC, J Biol Chem. 2006 Aug 18;281(33):23852-69. Epub 2006 May 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16675462 16675462]
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Type II site-specific deoxyribonuclease]]
[[Category: Bitinaite J]]
[[Category: Bitinaite, J.]]
[[Category: Chatwell L]]
[[Category: Chatwell, L.]]
[[Category: Etzkorn C]]
[[Category: Etzkorn, C.]]
[[Category: Horton NC]]
[[Category: Horton, N C.]]
[[Category: Joshi HK]]
[[Category: Joshi, H K.]]
[[Category: Dna intercalation]]
[[Category: Endonuclease]]
[[Category: Indirect readout]]
[[Category: Protein dna complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 04:17:08 2008''

Latest revision as of 12:28, 14 February 2024

Q138F HincII bound to cognate DNA GTCGAC and Ca2+Q138F HincII bound to cognate DNA GTCGAC and Ca2+

Structural highlights

2gih is a 4 chain structure with sequence from Haemophilus influenzae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

T2C2_HAEIF Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3.

See Also

2gih, resolution 2.50Å

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