2gic: Difference between revisions

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-{{Seed}}
-[[Image:2gic.png|left|200px]]
-<!--
+==Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex==
-The line below this paragraph, containing "STRUCTURE_2gic", creates the "Structure Box" on the page.
+<StructureSection load='2gic' size='340' side='right'caption='[[2gic]], [[Resolution|resolution]] 2.92&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2gic]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Vesicular_stomatitis_Indiana_virus Vesicular stomatitis Indiana virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GIC FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.92&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene></td></tr>
-{{STRUCTURE_2gic|  PDB=2gic  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gic OCA], [https://pdbe.org/2gic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gic RCSB], [https://www.ebi.ac.uk/pdbsum/2gic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gic ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NCAP_VSIVA NCAP_VSIVA] Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Replication is dependent on intracellular concentration of newly synthesized N, termed N(0), which corresponds to the protein not associated with RNA. In contrast, when associated with RNA, it is termed N. During replication, encapsidation by N(0) is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gi/2gic_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gic ConSurf].
+<div style="clear:both"></div>
-===Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex===
+==See Also==
+*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_16778022}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 16778022 is the PubMed ID number.
+[[Category: Vesicular stomatitis Indiana virus]]
--->
+[[Category: Green TJ]]
-{{ABSTRACT_PUBMED_16778022}}
+[[Category: Luo M]]
+[[Category: Wertz GW]]
-==About this Structure==
+[[Category: Zhang X]]
-GIC is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Vesicular_stomatitis_indiana_virus Vesicular stomatitis indiana virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIC OCA].
-==Reference==
-<ref group="xtra">PMID:16778022</ref><references group="xtra"/>
-[[Category: Vesicular stomatitis indiana virus]]
-[[Category: Green, T J.]]
-[[Category: Luo, M.]]
-[[Category: Wertz, G W.]]
-[[Category: Zhang, X.]]
-[[Category: Negative strand virus]]
-[[Category: Nucleocapsid]]
-[[Category: Protein-rna complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 23:48:59 2009''