2gf2: Difference between revisions

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-[[Image:2gf2.gif|left|200px]]
- {{Structure
+==Crystal structure of human hydroxyisobutyrate dehydrogenase==
-|PDB= 2gf2 |SIZE=350|CAPTION= <scene name='initialview01'>2gf2</scene>, resolution 2.38&Aring;
+<StructureSection load='2gf2' size='340' side='right'caption='[[2gf2]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[2gf2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GF2 FirstGlance]. <br>
-|ACTIVITY= [http://en.wikipedia.org/wiki/3-hydroxyisobutyrate_dehydrogenase 3-hydroxyisobutyrate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.31 1.1.1.31]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
-|GENE= HIBADH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf2 OCA], [https://pdbe.org/2gf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gf2 RCSB], [https://www.ebi.ac.uk/pdbsum/2gf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf2 ProSAT]</span></td></tr>
-}}
+</table>
+== Function ==
-'''Crystal structure of human hydroxyisobutyrate dehydrogenase'''
+[https://www.uniprot.org/uniprot/3HIDH_HUMAN 3HIDH_HUMAN]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
-==About this Structure==
+Check<jmol>
-GF2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF2 OCA].
+  <jmolCheckbox>
-[[Category: 3-hydroxyisobutyrate dehydrogenase]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf2_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gf2 ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Arrowsmith CH]]
-[[Category: Burgess, N.]]
+[[Category: Burgess N]]
-[[Category: Delft, F von.]]
+[[Category: Edwards AM]]
-[[Category: Edwards, A M.]]
+[[Category: Gileadi O]]
-[[Category: Gileadi, O.]]
+[[Category: Gorrec F]]
-[[Category: Gorrec, F.]]
+[[Category: Oppermann U]]
-[[Category: Oppermann, U.]]
+[[Category: Papagrigoriou E]]
-[[Category: Papagrigoriou, E.]]
+[[Category: Salah E]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Smee C]]
-[[Category: Salah, E.]]
+[[Category: Sundstrom M]]
-[[Category: Smee, C.]]
+[[Category: Turnbull AP]]
-[[Category: Sundstrom, M.]]
+[[Category: Weigelt J]]
-[[Category: Turnbull, A P.]]
+[[Category: Von Delft F]]
-[[Category: Weigelt, J.]]
-[[Category: dehydrogenase]]
-[[Category: sgc]]
-[[Category: structural genomic]]
-[[Category: structural genomics consortium]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:03:54 2008''

2gf2: Difference between revisions

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