2ge7: Difference between revisions

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[[Image:2ge7.png|left|200px]]


{{STRUCTURE_2ge7|  PDB=2ge7  |  SCENE=  }}
==Structure of the C-terminal dimerization domain of infectious bronchitis virus nucleocapsid protein==
 
<StructureSection load='2ge7' size='340' side='right'caption='[[2ge7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===Structure of the C-terminal dimerization domain of infectious bronchitis virus nucleocapsid protein===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ge7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Infectious_bronchitis_virus Infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GE7 FirstGlance]. <br>
{{ABSTRACT_PUBMED_16775348}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ge7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ge7 OCA], [https://pdbe.org/2ge7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ge7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ge7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ge7 ProSAT]</span></td></tr>
==About this Structure==
</table>
[[2ge7]] is a 2 chain structure of [[Nucleoprotein]] with sequence from [http://en.wikipedia.org/wiki/Infectious_bronchitis_virus Infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GE7 OCA].  
== Function ==
[https://www.uniprot.org/uniprot/NCAP_IBVG NCAP_IBVG] Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid. Interaction with the M protein leads to the formation of virus particles. Binds to cellular membranes and phospholipids. Elicits cell-mediated immunity. May play roles in viral transcription and translation, and/or replication.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ge/2ge7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ge7 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Nucleoprotein|Nucleoprotein]]
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016775348</ref><references group="xtra"/>
[[Category: Infectious bronchitis virus]]
[[Category: Infectious bronchitis virus]]
[[Category: Bowman, B R.]]
[[Category: Large Structures]]
[[Category: Collisson, E W.]]
[[Category: Bowman BR]]
[[Category: Fan, H.]]
[[Category: Collisson EW]]
[[Category: Jayaram, H.]]
[[Category: Fan H]]
[[Category: Jayaram, J.]]
[[Category: Jayaram H]]
[[Category: Lescar, J.]]
[[Category: Jayaram J]]
[[Category: Ooi, A.]]
[[Category: Lescar J]]
[[Category: Prasad, B V.]]
[[Category: Ooi A]]
[[Category: Coronavirus]]
[[Category: Prasad BV]]
[[Category: Dimerization domain]]
[[Category: Ibv n protein]]
[[Category: N protein]]
[[Category: Nucleocapsid protein]]
[[Category: Virus-viral protein-rna binding protein complex]]

Latest revision as of 12:27, 14 February 2024

Structure of the C-terminal dimerization domain of infectious bronchitis virus nucleocapsid proteinStructure of the C-terminal dimerization domain of infectious bronchitis virus nucleocapsid protein

Structural highlights

2ge7 is a 2 chain structure with sequence from Infectious bronchitis virus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NCAP_IBVG Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid. Interaction with the M protein leads to the formation of virus particles. Binds to cellular membranes and phospholipids. Elicits cell-mediated immunity. May play roles in viral transcription and translation, and/or replication.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2ge7, resolution 2.00Å

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