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[[Image:2fxq.gif|left|200px]]


{{Structure
==Single-stranded DNA-binding protein from Thermus aquaticus==
|PDB= 2fxq |SIZE=350|CAPTION= <scene name='initialview01'>2fxq</scene>, resolution 1.85&Aring;
<StructureSection load='2fxq' size='340' side='right'caption='[[2fxq]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2fxq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FXQ FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
|GENE= ssb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271 Thermus aquaticus])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fxq OCA], [https://pdbe.org/2fxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fxq RCSB], [https://www.ebi.ac.uk/pdbsum/2fxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fxq ProSAT]</span></td></tr>
}}
</table>
== Function ==
[https://www.uniprot.org/uniprot/SSB_THEAQ SSB_THEAQ]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fx/2fxq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fxq ConSurf].
<div style="clear:both"></div>


'''Single-stranded DNA-binding protein from Thermus aquaticus'''
==See Also==
 
*[[Single-stranded DNA-binding protein 3D structures|Single-stranded DNA-binding protein 3D structures]]
 
__TOC__
==Overview==
</StructureSection>
The crystal structure of the single-stranded DNA-binding protein from Thermus aquaticus has been solved and refined at 1.85 A resolution. Two monomers, each encompassing two oligonucleotide/oligosaccharide-binding (OB) domains and a number of flexible beta-hairpin loops, form an oligomer of approximate D(2) symmetry typical of bacterial SSBs. Comparison with other SSB structures confirms considerable variability in the mode of oligomerization and aggregation of SSB oligomers.
[[Category: Large Structures]]
 
==About this Structure==
2FXQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FXQ OCA].
 
==Reference==
Structure of the single-stranded DNA-binding protein SSB from Thermus aquaticus., Jedrzejczak R, Dauter M, Dauter Z, Olszewski M, Dlugolecka A, Kur J, Acta Crystallogr D Biol Crystallogr. 2006 Nov;62(Pt 11):1407-12. Epub 2006, Oct 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17057346 17057346]
[[Category: Single protein]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
[[Category: Dauter, M.]]
[[Category: Dauter M]]
[[Category: Dauter, Z.]]
[[Category: Dauter Z]]
[[Category: Jedrzejczak, R.]]
[[Category: Jedrzejczak R]]
[[Category: 5 strand beta-sheet extended loop]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:58:00 2008''

Latest revision as of 12:25, 14 February 2024

Single-stranded DNA-binding protein from Thermus aquaticusSingle-stranded DNA-binding protein from Thermus aquaticus

Structural highlights

2fxq is a 1 chain structure with sequence from Thermus aquaticus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SSB_THEAQ

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2fxq, resolution 1.85Å

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OCA
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