2fvo: Difference between revisions

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[[Image:2fvo.png|left|200px]]


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==Docking of the modified RF1 X-ray structure into the Low Resolution Cryo-EM map of E.coli 70S Ribosome bound with RF1==
The line below this paragraph, containing "STRUCTURE_2fvo", creates the "Structure Box" on the page.
<SX load='2fvo' size='340' side='right' viewer='molstar' caption='[[2fvo]], [[Resolution|resolution]] 12.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2fvo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FVO FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 12.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fvo OCA], [https://pdbe.org/2fvo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fvo RCSB], [https://www.ebi.ac.uk/pdbsum/2fvo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fvo ProSAT]</span></td></tr>
{{STRUCTURE_2fvo|  PDB=2fvo  |  SCENE=  }}
</table>
 
== Function ==
===Docking of the modified RF1 X-ray structure into the Low Resolution Cryo-EM map of E.coli 70S Ribosome bound with RF1===
[https://www.uniprot.org/uniprot/RF1_THEMA RF1_THEMA] Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity).
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/2fvo_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_16476444}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fvo ConSurf].
2FVO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVO OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</SX>
Interactions of the release factor RF1 with the ribosome as revealed by cryo-EM., Rawat U, Gao H, Zavialov A, Gursky R, Ehrenberg M, Frank J, J Mol Biol. 2006 Apr 7;357(4):1144-53. Epub 2006 Jan 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16476444 16476444]
[[Category: Large Structures]]
 
Structural analyses of peptide release factor 1 from Thermotoga maritima reveal domain flexibility required for its interaction with the ribosome., Shin DH, Brandsen J, Jancarik J, Yokota H, Kim R, Kim SH, J Mol Biol. 2004 Jul 30;341(1):227-39. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15312775 15312775]
[[Category: Single protein]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Ehrenberg, M.]]
[[Category: Ehrenberg M]]
[[Category: Frank, J.]]
[[Category: Frank J]]
[[Category: Gao, H.]]
[[Category: Gao H]]
[[Category: Gursky, R.]]
[[Category: Gursky R]]
[[Category: Rawat, U.]]
[[Category: Rawat U]]
[[Category: Zavialov, A.]]
[[Category: Zavialov A]]
[[Category: Rf1 ribosome cryo-em]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:51:19 2008''

Latest revision as of 12:25, 14 February 2024

Docking of the modified RF1 X-ray structure into the Low Resolution Cryo-EM map of E.coli 70S Ribosome bound with RF1Docking of the modified RF1 X-ray structure into the Low Resolution Cryo-EM map of E.coli 70S Ribosome bound with RF1

2fvo, resolution 12.80Å

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