2fhz: Difference between revisions

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[[Image:2fhz.png|left|200px]]


{{STRUCTURE_2fhz|  PDB=2fhz  |  SCENE=  }}
==Molecular Basis of Inhibition of the Ribonuclease Activity in Colicin E5 by Its Cognate Immunity Protein==
 
<StructureSection load='2fhz' size='340' side='right'caption='[[2fhz]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
===Molecular Basis of Inhibition of the Ribonuclease Activity in Colicin E5 by Its Cognate Immunity Protein===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2fhz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FHZ FirstGlance]. <br>
{{ABSTRACT_PUBMED_16524591}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fhz OCA], [https://pdbe.org/2fhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fhz RCSB], [https://www.ebi.ac.uk/pdbsum/2fhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fhz ProSAT]</span></td></tr>
==About this Structure==
</table>
[[2fhz]] is a 2 chain structure of [[Colicin]] and [[Colicin Immunity Protein]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FHZ OCA].  
== Function ==
[https://www.uniprot.org/uniprot/IMM5_ECOLX IMM5_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE5 encoding colicin E5, against colicin E5.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fh/2fhz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fhz ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Colicin|Colicin]]
*[[Colicin 3D structures|Colicin 3D structures]]
*[[Colicin Immunity Protein|Colicin Immunity Protein]]
*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016524591</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Huang, R H.]]
[[Category: Large Structures]]
[[Category: Lin, Y L.]]
[[Category: Huang RH]]
[[Category: Hydrolase]]
[[Category: Lin YL]]
[[Category: Immune system]]
[[Category: Inhibition of ribonuclease]]
[[Category: Protein-protein complex]]

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