2fgn: Difference between revisions

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-{{Seed}}
-[[Image:2fgn.png|left|200px]]
-<!--
+==Structural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein Variants==
-The line below this paragraph, containing "STRUCTURE_2fgn", creates the "Structure Box" on the page.
+<StructureSection load='2fgn' size='340' side='right'caption='[[2fgn]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2fgn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FGN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FGN FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_2fgn|  PDB=2fgn  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fgn OCA], [https://pdbe.org/2fgn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fgn RCSB], [https://www.ebi.ac.uk/pdbsum/2fgn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fgn ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PHLC_BACCE PHLC_BACCE] Required, with sphingomyelinase, to effect target cell lysis (hemolysis).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fg/2fgn_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fgn ConSurf].
+<div style="clear:both"></div>
-===Structural Studies Examining the Substrate Specificity Profiles of PC-PLCBc Protein Variants===
+==See Also==
+*[[Phospholipase C|Phospholipase C]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_17324372}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 17324372 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_17324372}}
-==About this Structure==
-FGN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FGN OCA].
-==Reference==
-Structural studies examining the substrate specificity profiles of PC-PLC(Bc) protein variants., Benfield AP, Goodey NM, Phillips LT, Martin SF, Arch Biochem Biophys. 2007 Apr 1;460(1):41-7. Epub 2007 Feb 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17324372 17324372]
 [[Category: Bacillus cereus]]
-[[Category: Phospholipase C]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Benfield AP]]
-[[Category: Benfield, A P.]]
+[[Category: Martin SF]]
-[[Category: Martin, S F.]]
-[[Category: Pc-plcbc protein variant]]
-[[Category: Substrate specificity]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 21:08:12 2008''