2ffl: Difference between revisions

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-[[Image:2ffl.png|left|200px]]
-{{STRUCTURE_2ffl|  PDB=2ffl  |  SCENE=  }}
+==Crystal Structure of Dicer from Giardia intestinalis==
+<StructureSection load='2ffl' size='340' side='right'caption='[[2ffl]], [[Resolution|resolution]] 3.33&Aring;' scene=''>
-===Crystal Structure of Dicer from Giardia intestinalis===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2ffl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Giardia_intestinalis Giardia intestinalis]. The February 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Small Interfering RNA''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_2 10.2210/rcsb_pdb/mom_2008_2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FFL FirstGlance]. <br>
-{{ABSTRACT_PUBMED_16410517}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.33&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ffl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ffl OCA], [https://pdbe.org/2ffl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ffl RCSB], [https://www.ebi.ac.uk/pdbsum/2ffl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ffl ProSAT]</span></td></tr>
-[[2ffl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Giardia_intestinalis Giardia intestinalis]. The February 2008 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Small Interfering RNA''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2008_2 10.2210/rcsb_pdb/mom_2008_2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFL OCA].
+</table>
+== Function ==
-==Reference==
+[https://www.uniprot.org/uniprot/DCL_GIAIC DCL_GIAIC] Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs.<ref>PMID:16410517</ref>
-<ref group="xtra">PMID:016410517</ref><ref group="xtra">PMID:018160966</ref><references group="xtra"/>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Giardia intestinalis]]
+[[Category: Large Structures]]
 [[Category: RCSB PDB Molecule of the Month]]
-[[Category: Ribonuclease III]]
 [[Category: Small Interfering RNA]]
-[[Category: Adams, P D.]]
+[[Category: Adams PD]]
-[[Category: Doudna, J A.]]
+[[Category: Doudna JA]]
-[[Category: MacRae, I J.]]
+[[Category: MacRae IJ]]
-[[Category: Hydrolase]]
-[[Category: Paz domain]]
-[[Category: Rna interference]]
-[[Category: Rnai]]
-[[Category: Translation]]