2f9m: Difference between revisions

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[[Image:2f9m.png|left|200px]]


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==3D structure of active human Rab11b GTPase==
The line below this paragraph, containing "STRUCTURE_2f9m", creates the "Structure Box" on the page.
<StructureSection load='2f9m' size='340' side='right'caption='[[2f9m]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2f9m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F9M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F9M FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
{{STRUCTURE_2f9m| PDB=2f9m |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f9m OCA], [https://pdbe.org/2f9m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f9m RCSB], [https://www.ebi.ac.uk/pdbsum/2f9m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f9m ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RB11B_HUMAN RB11B_HUMAN] GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f9/2f9m_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f9m ConSurf].
<div style="clear:both"></div>


===3D structure of active human Rab11b GTPase===
==See Also==
 
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
 
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{{ABSTRACT_PUBMED_16545962}}
 
==About this Structure==
2F9M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F9M OCA].
 
==Reference==
The crystal structure of the small GTPase Rab11b reveals critical differences relative to the Rab11a isoform., Scapin SM, Carneiro FR, Alves AC, Medrano FJ, Guimaraes BG, Zanchin NI, J Struct Biol. 2006 Jun;154(3):260-8. Epub 2006 Feb 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16545962 16545962]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Small monomeric GTPase]]
[[Category: Guimaraes BG]]
[[Category: Guimaraes, B G.]]
[[Category: Scapin SMN]]
[[Category: Scapin, S M.N]]
[[Category: Zanchin NIT]]
[[Category: Zanchin, N I.T.]]
[[Category: Rab11b gtpase]]
[[Category: Vesicle transport]]
 
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