2f0s: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2f0s.gif|left|200px]]<br /><applet load="2f0s" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="2f0s, resolution 1.75&Aring;" />
-'''Crystal structure of Staphylococcal nuclease mutant V66L/I92V'''<br />
-==About this Structure==
+==Crystal structure of Staphylococcal nuclease mutant V66L/I92V==
-F0S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Active as [http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2F0S OCA].
+<StructureSection load='2f0s' size='340' side='right'caption='[[2f0s]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-[[Category: Micrococcal nuclease]]
+== Structural highlights ==
-[[Category: Single protein]]
+<table><tr><td colspan='2'>[[2f0s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0S FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0s OCA], [https://pdbe.org/2f0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0s RCSB], [https://www.ebi.ac.uk/pdbsum/2f0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0s ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/2f0s_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f0s ConSurf].
+<div style="clear:both"></div>
+==See Also==
+*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Staphylococcus aureus]]
-[[Category: Lu, J.Z.]]
+[[Category: Lu JZ]]
-[[Category: Sakon, J.]]
+[[Category: Sakon J]]
-[[Category: Stites, W.E.]]
+[[Category: Stites WE]]
-[[Category: dna hydrolase; rna hydrolase; endonuclease; calcium; signal]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 10:17:04 2007''