2f0m: Difference between revisions

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New page: left|200px<br /><applet load="2f0m" size="450" color="white" frame="true" align="right" spinBox="true" caption="2f0m, resolution 2.00Å" /> '''Crystal structure of...
 
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[[Image:2f0m.jpg|left|200px]]<br /><applet load="2f0m" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2f0m, resolution 2.00&Aring;" />
'''Crystal structure of Staphylococcal nuclease mutant V23L/I72V'''<br />


==About this Structure==
==Crystal structure of Staphylococcal nuclease mutant V23L/I72V==
2F0M is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Active as [http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2F0M OCA].  
<StructureSection load='2f0m' size='340' side='right'caption='[[2f0m]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Micrococcal nuclease]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2f0m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0M FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0m OCA], [https://pdbe.org/2f0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0m RCSB], [https://www.ebi.ac.uk/pdbsum/2f0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0m ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/2f0m_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f0m ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Lu, J.Z.]]
[[Category: Lu JZ]]
[[Category: Sakon, J.]]
[[Category: Sakon J]]
[[Category: Stites, W.E.]]
[[Category: Stites WE]]
[[Category: dna hydrolase; rna hydrolase; endonuclease; calcium; signal]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 10:16:47 2007''

Latest revision as of 12:20, 14 February 2024

Crystal structure of Staphylococcal nuclease mutant V23L/I72VCrystal structure of Staphylococcal nuclease mutant V23L/I72V

Structural highlights

2f0m is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NUC_STAAU Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2f0m, resolution 2.00Å

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