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==T. brucei Farnesyl Diphosphate Synthase Complexed with Minodronate== | |||
<StructureSection load='2ewg' size='340' side='right'caption='[[2ewg]], [[Resolution|resolution]] 2.48Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2ewg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EWG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M0N:(1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC+ACID)'>M0N</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ewg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewg OCA], [https://pdbe.org/2ewg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ewg RCSB], [https://www.ebi.ac.uk/pdbsum/2ewg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ewg ProSAT]</span></td></tr> | ||
[[2ewg]] is a 2 chain structure | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q86C09_9TRYP Q86C09_9TRYP] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/2ewg_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ewg ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Farnesyl diphosphate synthase|Farnesyl diphosphate synthase]] | *[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: | |||
[[Category: Trypanosoma brucei]] | [[Category: Trypanosoma brucei]] | ||
[[Category: Cao | [[Category: Cao R]] | ||
[[Category: Gao | [[Category: Gao Y]] | ||
[[Category: Goddard | [[Category: Goddard A]] | ||
[[Category: Mao | [[Category: Mao J]] | ||
[[Category: Odeh | [[Category: Odeh S]] | ||
[[Category: Oldfield | [[Category: Oldfield E]] | ||
[[Category: Robinson | [[Category: Robinson H]] | ||
Latest revision as of 12:20, 14 February 2024
T. brucei Farnesyl Diphosphate Synthase Complexed with MinodronateT. brucei Farnesyl Diphosphate Synthase Complexed with Minodronate
Structural highlights
FunctionEvolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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