2esg: Difference between revisions

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-{{Seed}}
-[[Image:2esg.png|left|200px]]
-<!--
+==Solution structure of the complex between immunoglobulin IgA1 and human serum albumin==
-The line below this paragraph, containing "STRUCTURE_2esg", creates the "Structure Box" on the page.
+<StructureSection load='2esg' size='340' side='right'caption='[[2esg]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2esg]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ESG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ESG FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray solution scattering</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2esg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2esg OCA], [https://pdbe.org/2esg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2esg RCSB], [https://www.ebi.ac.uk/pdbsum/2esg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2esg ProSAT]</span></td></tr>
-{{STRUCTURE_2esg|  PDB=2esg  |  SCENE=  }}
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/IGHA1_HUMAN IGHA1_HUMAN] Note=A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.
+== Function ==
+[https://www.uniprot.org/uniprot/IGHA1_HUMAN IGHA1_HUMAN] Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/es/2esg_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2esg ConSurf].
+<div style="clear:both"></div>
-===Solution structure of the complex between immunoglobulin IgA1 and human serum albumin===
+==See Also==
+*[[Albumin 3D structures|Albumin 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_16376934}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 16376934 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_16376934}}
-==Disease==
-Known disease associated with this structure: Analbuminemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=103600 103600]], Dysalbuminemic hyperthyroxinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=103600 103600]], Dysalbuminemic hyperzincemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=103600 103600]]
-==About this Structure==
-ESG is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ESG OCA].
-==Reference==
-<ref group="xtra">PMID:16376934</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Almogren, A.]]
+[[Category: Large Structures]]
-[[Category: Furtado, P B.]]
+[[Category: Almogren A]]
-[[Category: Kerr, M A.]]
+[[Category: Furtado PB]]
-[[Category: Perkins, S J.]]
+[[Category: Kerr MA]]
-[[Category: Sun, Z.]]
+[[Category: Perkins SJ]]
-[[Category: Antibody]]
+[[Category: Sun Z]]
-[[Category: Human serum albumin]]
-[[Category: Immune system/transport protein complex]]
-[[Category: Immunoglobulin]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:32:41 2009''