2dgc: Difference between revisions

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{{Seed}}
[[Image:2dgc.png|left|200px]]


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==GCN4 BASIC DOMAIN, LEUCINE ZIPPER COMPLEXED WITH ATF/CREB SITE DNA==
The line below this paragraph, containing "STRUCTURE_2dgc", creates the "Structure Box" on the page.
<StructureSection load='2dgc' size='340' side='right'caption='[[2dgc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2dgc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DGC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DGC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dgc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dgc OCA], [https://pdbe.org/2dgc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dgc RCSB], [https://www.ebi.ac.uk/pdbsum/2dgc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dgc ProSAT]</span></td></tr>
{{STRUCTURE_2dgc| PDB=2dgc |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dg/2dgc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dgc ConSurf].
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===GCN4 BASIC DOMAIN, LEUCINE ZIPPER COMPLEXED WITH ATF/CREB SITE DNA===
==See Also==
 
*[[Gcn4|Gcn4]]
 
*[[Gcn4 3D Structures|Gcn4 3D Structures]]
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*[[Gnc4 3D Structures|Gnc4 3D Structures]]
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</StructureSection>
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_7500340}}
 
==About this Structure==
2DGC is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DGC OCA].
 
==Reference==
<ref group="xtra">PMID:7500340</ref><references group="xtra"/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Keller, W.]]
[[Category: Keller W]]
[[Category: Koenig, P.]]
[[Category: Koenig P]]
[[Category: Richmond, T J.]]
[[Category: Richmond TJ]]
[[Category: Basic domain]]
[[Category: Dna binding]]
[[Category: Eukaryotic regulatory protein]]
[[Category: Leucine zipper]]
 
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