2csn: Difference between revisions

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-[[Image:2csn.png|left|200px]]
-{{STRUCTURE_2csn|  PDB=2csn  |  SCENE=  }}
+==BINARY COMPLEX OF CASEIN KINASE-1 WITH CKI7==
+<StructureSection load='2csn' size='340' side='right'caption='[[2csn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-===BINARY COMPLEX OF CASEIN KINASE-1 WITH CKI7===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2csn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CSN FirstGlance]. <br>
-{{ABSTRACT_PUBMED_8692811}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CKI:N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE'>CKI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2csn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csn OCA], [https://pdbe.org/2csn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2csn RCSB], [https://www.ebi.ac.uk/pdbsum/2csn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2csn ProSAT]</span></td></tr>
-[[2csn]] is a 1 chain structure of [[Casein kinase]] with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSN OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CKI1_SCHPO CKI1_SCHPO] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/2csn_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2csn ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Casein kinase|Casein kinase]]
+*[[Casein kinase 3D structures|Casein kinase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:008692811</ref><references group="xtra"/>
+[[Category: Large Structures]]
 [[Category: Schizosaccharomyces pombe]]
-[[Category: Cheng, X.]]
+[[Category: Cheng X]]
-[[Category: Xu, R M.]]
+[[Category: Xu R-M]]
-[[Category: Casein kinase-1]]
-[[Category: Protein kinase]]