2chy: Difference between revisions

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[[Image:2chy.png|left|200px]]


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==THREE-DIMENSIONAL STRUCTURE OF CHEY, THE RESPONSE REGULATOR OF BACTERIAL CHEMOTAXIS==
The line below this paragraph, containing "STRUCTURE_2chy", creates the "Structure Box" on the page.
<StructureSection load='2chy' size='340' side='right'caption='[[2chy]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2chy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHY FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chy OCA], [https://pdbe.org/2chy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chy RCSB], [https://www.ebi.ac.uk/pdbsum/2chy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chy ProSAT]</span></td></tr>
{{STRUCTURE_2chy| PDB=2chy |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CHEY_SALTY CHEY_SALTY] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Shows autophosphatase activity which is enhanced by CheZ.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/2chy_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2chy ConSurf].
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===THREE-DIMENSIONAL STRUCTURE OF CHEY, THE RESPONSE REGULATOR OF BACTERIAL CHEMOTAXIS===
==See Also==
 
*[[Chemotaxis protein 3D structures|Chemotaxis protein 3D structures]]
 
*[[Receiver domain of sensor histidine kinase CKI1|Receiver domain of sensor histidine kinase CKI1]]
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[[Category: Large Structures]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
{{ABSTRACT_PUBMED_2645526}}
[[Category: Mottonen JM]]
 
[[Category: Schutt CE]]
==About this Structure==
[[Category: Stock AM]]
2CHY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHY OCA].
[[Category: Stock JB]]
 
==Reference==
Three-dimensional structure of CheY, the response regulator of bacterial chemotaxis., Stock AM, Mottonen JM, Stock JB, Schutt CE, Nature. 1989 Feb 23;337(6209):745-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2645526 2645526]
[[Category: Salmonella typhimurium]]
[[Category: Single protein]]
[[Category: Mottonen, J M.]]
[[Category: Schutt, C E.]]
[[Category: Stock, A M.]]
[[Category: Stock, J B.]]
[[Category: Signal transduction protein]]
 
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