2ba0: Difference between revisions

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[[Image:2ba0.png|left|200px]]


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==Archaeal exosome core==
The line below this paragraph, containing "STRUCTURE_2ba0", creates the "Structure Box" on the page.
<StructureSection load='2ba0' size='340' side='right'caption='[[2ba0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ba0]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BA0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ba0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ba0 OCA], [https://pdbe.org/2ba0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ba0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ba0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ba0 ProSAT]</span></td></tr>
{{STRUCTURE_2ba0| PDB=2ba0 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/RRP4_ARCFU RRP4_ARCFU] Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome (Probable).<ref>PMID:16285927</ref> <ref>PMID:20392821</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/2ba0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ba0 ConSurf].
<div style="clear:both"></div>


===Archaeal exosome core===
==See Also==
 
*[[Exosome 3D structures|Exosome 3D structures]]
 
== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 16285927 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_16285927}}
 
==About this Structure==
2BA0 is a 9 chains structure of sequences from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BA0 OCA].
 
==Reference==
<ref group="xtra">PMID:16285927</ref><references group="xtra"/>
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
[[Category: Buttner, K.]]
[[Category: Large Structures]]
[[Category: Hopfner, K P.]]
[[Category: Buttner K]]
[[Category: Wenig, K.]]
[[Category: Hopfner KP]]
[[Category: Archaeal]]
[[Category: Wenig K]]
[[Category: Exoribonuclease]]
[[Category: Exosome]]
[[Category: Kh domain]]
[[Category: Rna binding]]
[[Category: Rna degradation]]
[[Category: Rnase ph]]
[[Category: S1domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:50:55 2009''

Latest revision as of 12:16, 14 February 2024

Archaeal exosome coreArchaeal exosome core

Structural highlights

2ba0 is a 9 chain structure with sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RRP4_ARCFU Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome (Probable).[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Buttner K, Wenig K, Hopfner KP. Structural framework for the mechanism of archaeal exosomes in RNA processing. Mol Cell. 2005 Nov 11;20(3):461-71. PMID:16285927 doi:10.1016/j.molcel.2005.10.018
  2. Hartung S, Niederberger T, Hartung M, Tresch A, Hopfner KP. Quantitative analysis of processive RNA degradation by the archaeal RNA exosome. Nucleic Acids Res. 2010 Aug;38(15):5166-76. Epub 2010 Apr 14. PMID:20392821 doi:10.1093/nar/gkq238

2ba0, resolution 2.70Å

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