2ba0: Difference between revisions

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[[Image:2ba0.png|left|200px]]


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==Archaeal exosome core==
The line below this paragraph, containing "STRUCTURE_2ba0", creates the "Structure Box" on the page.
<StructureSection load='2ba0' size='340' side='right'caption='[[2ba0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ba0]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BA0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ba0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ba0 OCA], [https://pdbe.org/2ba0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ba0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ba0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ba0 ProSAT]</span></td></tr>
{{STRUCTURE_2ba0| PDB=2ba0 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/RRP4_ARCFU RRP4_ARCFU] Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome (Probable).<ref>PMID:16285927</ref> <ref>PMID:20392821</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/2ba0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ba0 ConSurf].
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===Archaeal exosome core===
==See Also==
 
*[[Exosome 3D structures|Exosome 3D structures]]
 
== References ==
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{{ABSTRACT_PUBMED_16285927}}
 
==About this Structure==
2BA0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BA0 OCA].
 
==Reference==
Structural framework for the mechanism of archaeal exosomes in RNA processing., Buttner K, Wenig K, Hopfner KP, Mol Cell. 2005 Nov 11;20(3):461-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16285927 16285927]
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Buttner, K.]]
[[Category: Buttner K]]
[[Category: Hopfner, K P.]]
[[Category: Hopfner KP]]
[[Category: Wenig, K.]]
[[Category: Wenig K]]
[[Category: Archaeal]]
[[Category: Exoribonuclease]]
[[Category: Exosome]]
[[Category: Kh domain]]
[[Category: Rna binding]]
[[Category: Rna degradation]]
[[Category: Rnase ph]]
[[Category: S1domain]]
 
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