2b72: Difference between revisions

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[[Image:2b72.png|left|200px]]


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==T4 Lysozyme mutant L99A at 100 MPa==
The line below this paragraph, containing "STRUCTURE_2b72", creates the "Structure Box" on the page.
<StructureSection load='2b72' size='340' side='right'caption='[[2b72]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2b72]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B72 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
{{STRUCTURE_2b72| PDB=2b72 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b72 OCA], [https://pdbe.org/2b72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b72 RCSB], [https://www.ebi.ac.uk/pdbsum/2b72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b72 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/2b72_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b72 ConSurf].
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===T4 Lysozyme mutant L99A at 100 MPa===
==See Also==
 
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
 
== References ==
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[[Category: Escherichia virus T4]]
{{ABSTRACT_PUBMED_16269539}}
[[Category: Large Structures]]
 
[[Category: Collins MD]]
==About this Structure==
[[Category: Gruner SM]]
2B72 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B72 OCA].
[[Category: Matthews BW]]
 
[[Category: Quillin ML]]
==Reference==
<ref group="xtra">PMID:16269539</ref><references group="xtra"/>
[[Category: Enterobacteria phage t4]]
[[Category: Lysozyme]]
[[Category: Collins, M D.]]
[[Category: Gruner, S M.]]
[[Category: Matthews, B W.]]
[[Category: Quillin, M L.]]
[[Category: Cavity]]
[[Category: High pressure]]
[[Category: T4 lysozyme]]
 
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