2b70: Difference between revisions

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-{{Seed}}
-[[Image:2b70.png|left|200px]]
-<!--
+==T4 Lysozyme mutant L99A at ambient pressure==
-The line below this paragraph, containing "STRUCTURE_2b70", creates the "Structure Box" on the page.
+<StructureSection load='2b70' size='340' side='right'caption='[[2b70]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2b70]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B70 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B70 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-{{STRUCTURE_2b70|  PDB=2b70  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b70 OCA], [https://pdbe.org/2b70 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b70 RCSB], [https://www.ebi.ac.uk/pdbsum/2b70 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b70 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/2b70_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b70 ConSurf].
+<div style="clear:both"></div>
-===T4 Lysozyme mutant L99A at ambient pressure===
+==See Also==
+*[[Lysozyme 3D structures|Lysozyme 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_16269539}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 16269539 is the PubMed ID number.
+</StructureSection>
--->
+[[Category: Escherichia virus T4]]
-{{ABSTRACT_PUBMED_16269539}}
+[[Category: Large Structures]]
+[[Category: Collins MD]]
-==About this Structure==
+[[Category: Gruner SM]]
-B70 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B70 OCA].
+[[Category: Matthews BW]]
+[[Category: Quillin ML]]
-==Reference==
-Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation., Collins MD, Hummer G, Quillin ML, Matthews BW, Gruner SM, Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16668-71. Epub 2005 Nov 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16269539 16269539]
-[[Category: Enterobacteria phage t4]]
-[[Category: Lysozyme]]
-[[Category: Collins, M D.]]
-[[Category: Gruner, S M.]]
-[[Category: Matthews, B W.]]
-[[Category: Quillin, M L.]]
-[[Category: TBSGC, TB Structural Genomics Consortium.]]
-[[Category: High pressure]]
-[[Category: Protein structure initiative]]
-[[Category: Psi]]
-[[Category: Structural genomic]]
-[[Category: T4 lysozyme]]
-[[Category: Tb structural genomics consortium]]
-[[Category: Tbsgc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 09:43:08 2008''