2b6x: Difference between revisions

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[[Image:2b6x.png|left|200px]]


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==T4 Lysozyme mutant L99A at 200 MPa==
The line below this paragraph, containing "STRUCTURE_2b6x", creates the "Structure Box" on the page.
<StructureSection load='2b6x' size='340' side='right'caption='[[2b6x]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2b6x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B6X FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.107&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
{{STRUCTURE_2b6x| PDB=2b6x |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b6x OCA], [https://pdbe.org/2b6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b6x RCSB], [https://www.ebi.ac.uk/pdbsum/2b6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b6x ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/2b6x_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b6x ConSurf].
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===T4 Lysozyme mutant L99A at 200 MPa===
==See Also==
 
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
 
== References ==
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[[Category: Escherichia virus T4]]
{{ABSTRACT_PUBMED_16269539}}
[[Category: Large Structures]]
 
[[Category: Collins MD]]
==About this Structure==
[[Category: Gruner SM]]
2B6X is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6X OCA].
[[Category: Matthews BW]]
 
[[Category: Quillin ML]]
==Reference==
<ref group="xtra">PMID:16269539</ref><references group="xtra"/>
[[Category: Enterobacteria phage t4]]
[[Category: Lysozyme]]
[[Category: Collins, M D.]]
[[Category: Gruner, S M.]]
[[Category: Matthews, B W.]]
[[Category: Quillin, M L.]]
[[Category: High pressure]]
[[Category: T4 lysozyme]]
 
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