2b2a: Difference between revisions

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OCA

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-[[Image:2b2a.png|left|200px]]
-<!--
+==Crystal Structure of the TEN domain of the Telomerase Reverse Transcriptase==
-The line below this paragraph, containing "STRUCTURE_2b2a", creates the "Structure Box" on the page.
+<StructureSection load='2b2a' size='340' side='right'caption='[[2b2a]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2b2a]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B2A FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2a OCA], [https://pdbe.org/2b2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b2a RCSB], [https://www.ebi.ac.uk/pdbsum/2b2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b2a ProSAT]</span></td></tr>
-{{STRUCTURE_2b2a|  PDB=2b2a  |  SCENE=  }}
+</table>
+== Function ==
-===Crystal Structure of the TEN domain of the Telomerase Reverse Transcriptase===
+[https://www.uniprot.org/uniprot/TERT_TETTS TERT_TETTS] Catalytic component of telomerase, an essential ribonucleoprotein enzyme that copies new telomeric repeats onto chromosome ends by repetitively synthesizing the short telomere-repeat sequence 5'-TTGGGG-3' using an RNA template component TER (PubMed:10944124, PubMed:15696174, PubMed:17322903, PubMed:20713447, PubMed:16462747). TERT is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme (PubMed:10944124, PubMed:15696174, PubMed:17322903, PubMed:20713447, PubMed:16462747).<ref>PMID:10944124</ref> <ref>PMID:15696174</ref> <ref>PMID:16462747</ref> <ref>PMID:17322903</ref> <ref>PMID:20713447</ref>
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_16462747}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 16462747 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_16462747}}
-==About this Structure==
-[[2b2a]] is a 3 chain structure of [[Reverse transcriptase]], [[Telomerase]] and [[Telomerase Reverse Transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2A OCA].
 ==See Also==
-*[[Reverse transcriptase|Reverse transcriptase]]
+*[[Telomerase 3D structures|Telomerase 3D structures]]
-*[[Telomerase|Telomerase]]
 *[[Telomerase Reverse Transcriptase|Telomerase Reverse Transcriptase]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:016462747</ref><references group="xtra"/>
+__TOC__
-[[Category: RNA-directed DNA polymerase]]
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Tetrahymena thermophila]]
-[[Category: Cech, T R.]]
+[[Category: Cech TR]]
-[[Category: Jacobs, S A.]]
+[[Category: Jacobs SA]]
-[[Category: Podell, E R.]]
+[[Category: Podell ER]]
-[[Category: Reverse transcriptase]]
-[[Category: Rt]]
-[[Category: Telomerase]]
-[[Category: Tert]]
-[[Category: Transferase]]