2b26: Difference between revisions

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[[Image:2b26.png|left|200px]]


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==The crystal structure of the protein complex of yeast Hsp40 Sis1 and Hsp70 Ssa1==
The line below this paragraph, containing "STRUCTURE_2b26", creates the "Structure Box" on the page.
<StructureSection load='2b26' size='340' side='right'caption='[[2b26]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2b26]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B26 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b26 OCA], [https://pdbe.org/2b26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b26 RCSB], [https://www.ebi.ac.uk/pdbsum/2b26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b26 ProSAT]</span></td></tr>
{{STRUCTURE_2b26|  PDB=2b26  |  SCENE=  }}
</table>
 
== Function ==
===The crystal structure of the protein complex of yeast Hsp40 Sis1 and Hsp70 Ssa1===
[https://www.uniprot.org/uniprot/SIS1_YEAST SIS1_YEAST] Required for nuclear migration during mitosis. It is required for the normal initiation of translation. Might mediate the dissociation of a specific protein complex of the translation machinery. Essential for viability.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b26 ConSurf].
2B26 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B26 OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
Crystal structure of yeast Sis1 peptide-binding fragment and Hsp70 Ssa1 C-terminal complex., Li J, Wu Y, Qian X, Sha B, Biochem J. 2006 Sep 15;398(3):353-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16737444 16737444]
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Li, J.]]
[[Category: Li J]]
[[Category: Qian, X.]]
[[Category: Qian X]]
[[Category: Sha, B.]]
[[Category: Sha B]]
[[Category: Wu, Y.]]
[[Category: Wu Y]]
[[Category: Hsp40 sis1 hsp70 ssa1]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 10:52:41 2008''

Latest revision as of 12:15, 14 February 2024

The crystal structure of the protein complex of yeast Hsp40 Sis1 and Hsp70 Ssa1The crystal structure of the protein complex of yeast Hsp40 Sis1 and Hsp70 Ssa1

Structural highlights

2b26 is a 4 chain structure with sequence from Drosophila melanogaster and Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SIS1_YEAST Required for nuclear migration during mitosis. It is required for the normal initiation of translation. Might mediate the dissociation of a specific protein complex of the translation machinery. Essential for viability.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2b26, resolution 3.20Å

Drag the structure with the mouse to rotate

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