2a11: Difference between revisions

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[[Image:2a11.png|left|200px]]


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==Crystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium Tuberculosis==
The line below this paragraph, containing "STRUCTURE_2a11", creates the "Structure Box" on the page.
<StructureSection load='2a11' size='340' side='right'caption='[[2a11]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2a11]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A11 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_2a11| PDB=2a11 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a11 OCA], [https://pdbe.org/2a11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a11 RCSB], [https://www.ebi.ac.uk/pdbsum/2a11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a11 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNC_MYCTU RNC_MYCTU] Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).[HAMAP-Rule:MF_00104]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/2a11_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a11 ConSurf].
<div style="clear:both"></div>


===Crystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium Tuberculosis===
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_16155207}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 16155207 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16155207}}
 
==About this Structure==
2A11 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A11 OCA].
 
==Reference==
<ref group="xtra">PMID:16155207</ref><references group="xtra"/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Ribonuclease III]]
[[Category: Akey DL]]
[[Category: Akey, D L.]]
[[Category: Berger JM]]
[[Category: Berger, J M.]]
[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project.]]
[[Category: Nuclease domain]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Ribonuclease]]
[[Category: Rnase iii]]
[[Category: Structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:10:26 2009''

Latest revision as of 12:10, 14 February 2024

Crystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium TuberculosisCrystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium Tuberculosis

Structural highlights

2a11 is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNC_MYCTU Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).[HAMAP-Rule:MF_00104]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2a11, resolution 2.10Å

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