2a11: Difference between revisions

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[[Image:2a11.png|left|200px]]


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==Crystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium Tuberculosis==
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<StructureSection load='2a11' size='340' side='right'caption='[[2a11]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2a11]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A11 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_2a11|  PDB=2a11  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a11 OCA], [https://pdbe.org/2a11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a11 RCSB], [https://www.ebi.ac.uk/pdbsum/2a11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a11 ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium Tuberculosis===
== Function ==
 
[https://www.uniprot.org/uniprot/RNC_MYCTU RNC_MYCTU] Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).[HAMAP-Rule:MF_00104]
 
== Evolutionary Conservation ==
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==About this Structure==
  </jmolCheckbox>
[[2a11]] is a 1 chain structure of [[Ribonuclease]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A11 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a11 ConSurf].
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==See Also==
==See Also==
*[[Ribonuclease]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016155207</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Ribonuclease III]]
[[Category: Akey DL]]
[[Category: Akey, D L.]]
[[Category: Berger JM]]
[[Category: Berger, J M.]]
[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project.]]
[[Category: Hydrolase]]
[[Category: Nuclease domain]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Ribonuclease]]
[[Category: Rnase iii]]
[[Category: Structural genomic]]
[[Category: Transcription]]
[[Category: Translation]]

Latest revision as of 12:10, 14 February 2024

Crystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium TuberculosisCrystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium Tuberculosis

Structural highlights

2a11 is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNC_MYCTU Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).[HAMAP-Rule:MF_00104]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2a11, resolution 2.10Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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