237d: Difference between revisions

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[[Image:237d.jpg|left|200px]]


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==CRYSTAL STRUCTURE OF A DNA DECAMER SHOWING A NOVEL PSEUDO FOUR-WAY HELIX-HELIX JUNCTION==
The line below this paragraph, containing "STRUCTURE_237d", creates the "Structure Box" on the page.
<StructureSection load='237d' size='340' side='right'caption='[[237d]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[237d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=237D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=237D FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=237d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=237d OCA], [https://pdbe.org/237d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=237d RCSB], [https://www.ebi.ac.uk/pdbsum/237d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=237d ProSAT]</span></td></tr>
{{STRUCTURE_237d|  PDB=237d  |  SCENE= }}
</table>
 
__TOC__
'''CRYSTAL STRUCTURE OF A DNA DECAMER SHOWING A NOVEL PSEUDO FOUR-WAY HELIX-HELIX JUNCTION'''
</StructureSection>
 
[[Category: Large Structures]]
 
[[Category: Berman HM]]
==Overview==
[[Category: Neidle S]]
The crystal structure of the decanucleotide d(CGCAATTGCG)2 has been solved by a combination of molecular replacement and heavy-atom procedures and has been refined to an R factor of 20.2% at 2.7 A. It is not a fully base-paired duplex but has a central core of eight Watson-Crick base pairs flanked by unpaired terminal guanosines and cytosines. These participate in hydrogen-bonding arrangements with adjacent decamer duplexes in the crystal lattice. The unpaired guanosines are bound in the G+C regions of duplex minor grooves. The cytosines have relatively high mobility, even though they are constrained to be in one region where they are involved in base-paired triplets with G.C base pairs. The 5'-AATT sequence in the duplex region has a narrow minor groove, providing further confirmation of the sequence-dependent nature of groove width.
[[Category: Nunn CM]]
 
[[Category: Spink N]]
==About this Structure==
[[Category: Vojtechovsky J]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=237D OCA].  
 
==Reference==
Crystal structure of a DNA decamer showing a novel pseudo four-way helix-helix junction., Spink N, Nunn CM, Vojtechovsky J, Berman HM, Neidle S, Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10767-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7479880 7479880]
[[Category: Berman, H M.]]
[[Category: Neidle, S.]]
[[Category: Nunn, C M.]]
[[Category: Spink, N.]]
[[Category: Vojtechovsky, J.]]
[[Category: B-dna]]
[[Category: Double helix]]
[[Category: Flipped-out base]]
[[Category: Intermolecular base triplet]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 18:21:38 2008''

Latest revision as of 12:09, 14 February 2024

CRYSTAL STRUCTURE OF A DNA DECAMER SHOWING A NOVEL PSEUDO FOUR-WAY HELIX-HELIX JUNCTIONCRYSTAL STRUCTURE OF A DNA DECAMER SHOWING A NOVEL PSEUDO FOUR-WAY HELIX-HELIX JUNCTION

Structural highlights

237d is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

237d, resolution 2.50Å

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