210d: Difference between revisions

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[[Image:210d.gif|left|200px]]


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==CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A)CG] AND ITS PLATINATED DERIVATIVE==
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<StructureSection load='210d' size='340' side='right'caption='[[210d]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[210d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=210D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=210D FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
{{STRUCTURE_210d|  PDB=210d  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=210d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=210d OCA], [https://pdbe.org/210d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=210d RCSB], [https://www.ebi.ac.uk/pdbsum/210d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=210d ProSAT]</span></td></tr>
 
</table>
'''CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A)CG] AND ITS PLATINATED DERIVATIVE'''
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</StructureSection>
 
[[Category: Large Structures]]
==Overview==
[[Category: Arvantis GM]]
The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous with other DNA hexanucleotides. Despite completely different crystal packing, the essential characteristics of the Z-DNA conformation are maintained. The structure was determined by single isomorphous replacement using a triammine platinum fragment. Thus, this study also demonstrates, for the first time, the feasibility of the use of this reagent for the direct phasing of DNA crystal structures.
[[Category: Berman HM]]
 
[[Category: Gaffney B]]
==About this Structure==
[[Category: Ginell SL]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=210D OCA].  
[[Category: Jones R]]
 
[[Category: Lessinger L]]
==Reference==
[[Category: Parkinson GN]]
Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7492550 7492550]
[[Category: Arvantis, G M.]]
[[Category: Berman, H M.]]
[[Category: Gaffney, B.]]
[[Category: Ginell, S L.]]
[[Category: Jones, R.]]
[[Category: Lessinger, L.]]
[[Category: Parkinson, G N.]]
[[Category: Double helix]]
[[Category: Modified]]
[[Category: Z-dna]]
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