1zhi: Difference between revisions

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[[Image:1zhi.png|left|200px]]


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==Complex of the S. cerevisiae Orc1 and Sir1 interacting domains==
The line below this paragraph, containing "STRUCTURE_1zhi", creates the "Structure Box" on the page.
<StructureSection load='1zhi' size='340' side='right'caption='[[1zhi]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1zhi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZHI FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zhi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zhi OCA], [https://pdbe.org/1zhi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zhi RCSB], [https://www.ebi.ac.uk/pdbsum/1zhi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zhi ProSAT]</span></td></tr>
{{STRUCTURE_1zhi|  PDB=1zhi  |  SCENE=  }}
</table>
 
== Function ==
===Complex of the S. cerevisiae Orc1 and Sir1 interacting domains===
[https://www.uniprot.org/uniprot/ORC1_YEAST ORC1_YEAST] Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication.<ref>PMID:17825064</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zh/1zhi_consurf.spt"</scriptWhenChecked>
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zhi ConSurf].
1ZHI is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZHI OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing., Hou Z, Bernstein DA, Fox CA, Keck JL, Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8489-94. Epub 2005 Jun 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15932939 15932939]
__TOC__
[[Category: Protein complex]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Bernstein, D A.]]
[[Category: Bernstein DA]]
[[Category: Fox, C A.]]
[[Category: Fox CA]]
[[Category: Hou, Z.]]
[[Category: Hou Z]]
[[Category: Keck, J L.]]
[[Category: Keck JL]]
[[Category: Bah domain]]
[[Category: Oir domain]]
[[Category: Protein complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat Jul  5 16:22:17 2008''

Latest revision as of 12:05, 14 February 2024

Complex of the S. cerevisiae Orc1 and Sir1 interacting domainsComplex of the S. cerevisiae Orc1 and Sir1 interacting domains

Structural highlights

1zhi is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ORC1_YEAST Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Asano T, Makise M, Takehara M, Mizushima T. Interaction between ORC and Cdt1p of Saccharomyces cerevisiae. FEMS Yeast Res. 2007 Dec;7(8):1256-62. Epub 2007 Sep 6. PMID:17825064 doi:http://dx.doi.org/10.1111/j.1567-1364.2007.00299.x

1zhi, resolution 2.70Å

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