1z7n: Difference between revisions

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{{Seed}}
[[Image:1z7n.png|left|200px]]


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==ATP Phosphoribosyl transferase (HisZG ATP-PRTase) from Lactococcus lactis with bound PRPP substrate==
The line below this paragraph, containing "STRUCTURE_1z7n", creates the "Structure Box" on the page.
<StructureSection load='1z7n' size='340' side='right'caption='[[1z7n]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1z7n]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z7N FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr>
{{STRUCTURE_1z7n| PDB=1z7n |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z7n OCA], [https://pdbe.org/1z7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z7n RCSB], [https://www.ebi.ac.uk/pdbsum/1z7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z7n ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HISZ_LACLA HISZ_LACLA] Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.[HAMAP-Rule:MF_00125]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/1z7n_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z7n ConSurf].
<div style="clear:both"></div>


===ATP Phosphoribosyl transferase (HisZG ATP-PRTase) from Lactococcus lactis with bound PRPP substrate===
==See Also==
 
*[[ATP Phosphoribosyl Transferase|ATP Phosphoribosyl Transferase]]
 
*[[ATP phosphoribosyl transferase 3D structures|ATP phosphoribosyl transferase 3D structures]]
==About this Structure==
__TOC__
1Z7N is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z7N OCA].
</StructureSection>
[[Category: ATP phosphoribosyltransferase]]
[[Category: Lactococcus lactis]]
[[Category: Lactococcus lactis]]
[[Category: Champagne, K S.]]
[[Category: Large Structures]]
[[Category: Doublie, S.]]
[[Category: Champagne KS]]
[[Category: Francklyn, C S.]]
[[Category: Doublie S]]
[[Category: Larrabee, Y.]]
[[Category: Francklyn CS]]
[[Category: Sissler, M.]]
[[Category: Larrabee Y]]
[[Category: Allosteric]]
[[Category: Sissler M]]
[[Category: Atp-prt]]
[[Category: Histidine biosynthesis]]
[[Category: Hiszg]]
[[Category: Prpp]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:56:26 2009''

Latest revision as of 12:02, 14 February 2024

ATP Phosphoribosyl transferase (HisZG ATP-PRTase) from Lactococcus lactis with bound PRPP substrateATP Phosphoribosyl transferase (HisZG ATP-PRTase) from Lactococcus lactis with bound PRPP substrate

Structural highlights

1z7n is a 8 chain structure with sequence from Lactococcus lactis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.25Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HISZ_LACLA Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.[HAMAP-Rule:MF_00125]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1z7n, resolution 3.25Å

Drag the structure with the mouse to rotate

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OCA
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