1yt1: Difference between revisions

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-[[Image:1yt1.png|left|200px]]
-<!--
+==Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL==
-The line below this paragraph, containing "STRUCTURE_1yt1", creates the "Structure Box" on the page.
+<StructureSection load='1yt1' size='340' side='right'caption='[[1yt1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1yt1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YT1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YT1 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
-{{STRUCTURE_1yt1|  PDB=1yt1  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yt1 OCA], [https://pdbe.org/1yt1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yt1 RCSB], [https://www.ebi.ac.uk/pdbsum/1yt1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yt1 ProSAT]</span></td></tr>
+</table>
-===Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL===
+== Function ==
+[https://www.uniprot.org/uniprot/ENPL_CANLF ENPL_CANLF] Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity).
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_15951571}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 15951571 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yt/1yt1_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_15951571}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-[[1yt1]] is a 2 chain structure of [[Endoplasmin]] with sequence from [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YT1 OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yt1 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Endoplasmin]]
+*[[Heat Shock Protein structures|Heat Shock Protein structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:15951571</ref><references group="xtra"/>
 [[Category: Canis lupus familiaris]]
-[[Category: Dollins, D E.]]
+[[Category: Large Structures]]
-[[Category: Gewirth, D T.]]
+[[Category: Dollins DE]]
-[[Category: Immormino, R M.]]
+[[Category: Gewirth DT]]
-[[Category: Bergerat]]
+[[Category: Immormino RM]]
-[[Category: Chaperone]]
-[[Category: Endoplasmic reticulum]]
-[[Category: Gp96]]
-[[Category: Grp94]]
-[[Category: Hsp90]]
-[[Category: Htpg]]