1yfg: Difference between revisions

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OCA

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-[[Image:1yfg.gif|left|200px]]<br />
-<applet load="1yfg" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1yfg, resolution 3.000&Aring;" />
-'''YEAST INITIATOR TRNA'''<br />
-==Overview==
+==YEAST INITIATOR TRNA==
-A significantly improved molecular model of yeast initiator tRNA, (ytRNA(iMet) has been prepared that gives insight into the structural, basis of eukaryotic initiator tRNA's unique function. This study was made, possible by X-ray data collected at synchrotron radiation sources with the, newly developed technologies of 'imaging plates' and 'storage phosphors'., These data extend beyond the resolution limit of 4.0 A reported previously, to a current limit of 3.0 A and are considerably more accurate. Refinement, of the model against the new data (R factor = 21.5%) clearly reveals a, novel modification and a set of tertiary interactions involving sequence, features characteristic of eukaryotic initiator tRNAs. We hypothesize, these to be the structural elements responsible for part of the special, function of yeast tRNA(iMET).
+<StructureSection load='1yfg' size='340' side='right'caption='[[1yfg]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1yfg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The March 2001 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Transfer RNA''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2001_3 10.2210/rcsb_pdb/mom_2001_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YFG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YFG FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=1MG:1N-METHYLGUANOSINE-5-MONOPHOSPHATE'>1MG</scene>, <scene name='pdbligand=2MG:2N-METHYLGUANOSINE-5-MONOPHOSPHATE'>2MG</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=7MG:7N-METHYL-8-HYDROGUANOSINE-5-MONOPHOSPHATE'>7MG</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=M2G:N2-DIMETHYLGUANOSINE-5-MONOPHOSPHATE'>M2G</scene>, <scene name='pdbligand=RIA:2-O-[(5-PHOSPHO)RIBOSYL]ADENOSINE-5-MONOPHOSPHATE'>RIA</scene>, <scene name='pdbligand=T6A:N-[N-(9-B-D-RIBOFURANOSYLPURIN-6-YL)CARBAMOYL]THREONINE-5-MONOPHOSPHATE'>T6A</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yfg OCA], [https://pdbe.org/1yfg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yfg RCSB], [https://www.ebi.ac.uk/pdbsum/1yfg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yfg ProSAT]</span></td></tr>
+</table>
-==About this Structure==
+==See Also==
-YFG is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The following page contains interesting information on the relation of 1YFG with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb15_1.html Transfer RNA]]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1YFG OCA].
+*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
+__TOC__
-==Reference==
+</StructureSection>
-The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination., Basavappa R, Sigler PB, EMBO J. 1991 Oct;10(10):3105-11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1915284 1915284]
+[[Category: Large Structures]]
-[[Category: Protein complex]]
+[[Category: RCSB PDB Molecule of the Month]]
 [[Category: Saccharomyces cerevisiae]]
 [[Category: Transfer RNA]]
-[[Category: Basavappa, R.]]
+[[Category: Basavappa R]]
-[[Category: Sigler, P.B.]]
+[[Category: Sigler PB]]
-[[Category: amino acid transport]]
-[[Category: transfer ribonucleic acid]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Thu Nov  8 12:45:49 2007''