1xwf: Difference between revisions

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-{{Seed}}
-[[Image:1xwf.png|left|200px]]
-<!--
+==K185N mutated S-adenosylhomocysteine hydrolase==
-The line below this paragraph, containing "STRUCTURE_1xwf", creates the "Structure Box" on the page.
+<StructureSection load='1xwf' size='340' side='right'caption='[[1xwf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1xwf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XWF FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
-{{STRUCTURE_1xwf|  PDB=1xwf  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xwf OCA], [https://pdbe.org/1xwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xwf RCSB], [https://www.ebi.ac.uk/pdbsum/1xwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xwf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SAHH_RAT SAHH_RAT] Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xw/1xwf_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xwf ConSurf].
+<div style="clear:both"></div>
-===K185N mutated S-adenosylhomocysteine hydrolase===
+==See Also==
+*[[S-adenosylhomocysteine hydrolase|S-adenosylhomocysteine hydrolase]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_16061414}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 16061414 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_16061414}}
-==About this Structure==
-XWF is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XWF OCA].
-==Reference==
-<ref group="xtra">PMID:16061414</ref><references group="xtra"/>
-[[Category: Adenosylhomocysteinase]]
 [[Category: Rattus norvegicus]]
-[[Category: Fujioka, M.]]
+[[Category: Fujioka M]]
-[[Category: Gomi, T.]]
+[[Category: Gomi T]]
-[[Category: Komoto, J.]]
+[[Category: Komoto J]]
-[[Category: Ogawa, H.]]
+[[Category: Ogawa H]]
-[[Category: Takata, Y.]]
+[[Category: Takata Y]]
-[[Category: Takusagawa, F.]]
+[[Category: Takusagawa F]]
-[[Category: Yamada, T.]]
+[[Category: Yamada T]]
-[[Category: Adohcy hydrolase]]
-[[Category: Adohcyase]]
-[[Category: S-adenosylhomocysteine hydrolase]]
-[[Category: Sahh]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:13:10 2009''