1xrc: Difference between revisions

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-[[Image:1xrc.png|left|200px]]
-{{STRUCTURE_1xrc|  PDB=1xrc  |  SCENE=  }}
+==CRYSTAL STRUCTURE OF S-ADENOSYLMETHIONINE SYNTHETASE==
+<StructureSection load='1xrc' size='340' side='right'caption='[[1xrc]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-===CRYSTAL STRUCTURE OF S-ADENOSYLMETHIONINE SYNTHETASE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1xrc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XRC FirstGlance]. <br>
-{{ABSTRACT_PUBMED_8550549}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xrc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xrc OCA], [https://pdbe.org/1xrc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xrc RCSB], [https://www.ebi.ac.uk/pdbsum/1xrc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xrc ProSAT]</span></td></tr>
-[[1xrc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XRC OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/METK_ECOLI METK_ECOLI] Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. Is essential for growth.[HAMAP-Rule:MF_00086]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xr/1xrc_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xrc ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[S-adenosylmethionine synthetase|S-adenosylmethionine synthetase]]
+*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:008550549</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Methionine adenosyltransferase]]
+[[Category: Large Structures]]
-[[Category: Kamitori, S.]]
+[[Category: Kamitori S]]
-[[Category: Markham, G D.]]
+[[Category: Markham GD]]
-[[Category: Misaki, S.]]
+[[Category: Misaki S]]
-[[Category: Takusagawa, F.]]
+[[Category: Takusagawa F]]
-[[Category: Methyltransferase]]