1xlt: Difference between revisions

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[[Image:1xlt.png|left|200px]]


{{STRUCTURE_1xlt| PDB=1xlt | SCENE= }}
==Crystal structure of Transhydrogenase [(domain I)2:domain III] heterotrimer complex==
<StructureSection load='1xlt' size='340' side='right'caption='[[1xlt]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1xlt]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodospirillum_rubrum Rhodospirillum rubrum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XLT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XLT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xlt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xlt OCA], [https://pdbe.org/1xlt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xlt RCSB], [https://www.ebi.ac.uk/pdbsum/1xlt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xlt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PNTAA_RHORT PNTAA_RHORT] The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.[UniProtKB:P07001]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xl/1xlt_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xlt ConSurf].
<div style="clear:both"></div>


===Crystal structure of Transhydrogenase [(domain I)2:domain III] heterotrimer complex===
==See Also==
 
*[[NAD(P) transhydrogenase 3D structures|NAD(P) transhydrogenase 3D structures]]
{{ABSTRACT_PUBMED_15670609}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[1xlt]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodospirillum_rubrum Rhodospirillum rubrum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XLT OCA].
 
==Reference==
<ref group="xtra">PMID:015670609</ref><references group="xtra"/>
[[Category: Rhodospirillum rubrum]]
[[Category: Rhodospirillum rubrum]]
[[Category: Chartron, J.]]
[[Category: Chartron J]]
[[Category: Stout, C D.]]
[[Category: Stout CD]]
[[Category: Sundaresan, V.]]
[[Category: Sundaresan V]]
[[Category: Yamaguchi, M.]]
[[Category: Yamaguchi M]]
[[Category: Nad]]
[[Category: Nadh]]
[[Category: Nadp]]
[[Category: Nadph]]
[[Category: Oxidoreductase]]
[[Category: Transhydrogenase]]

Latest revision as of 11:51, 14 February 2024

Crystal structure of Transhydrogenase [(domain I)2:domain III] heterotrimer complexCrystal structure of Transhydrogenase [(domain I)2:domain III] heterotrimer complex

Structural highlights

1xlt is a 9 chain structure with sequence from Rhodospirillum rubrum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.1Å
Ligands:, , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PNTAA_RHORT The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.[UniProtKB:P07001]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1xlt, resolution 3.10Å

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